Fungal peroxidases: molecular aspects and applications

TitleFungal peroxidases: molecular aspects and applications
Publication TypeJournal Article
Year of Publication2002
AuthorsConesa, A, Punt, PJ, van den Hondel, CA
JournalJ Biotechnol
KeywordsAmino Acid Sequence Binding Sites Biotechnology Catalysis Fungi/*enzymology Molecular Sequence Data Peroxidases/chemistry/*genetics/metabolism Recombinant Proteins Sequence Homology Substrate Specificity

Peroxidases are oxidoreductases that utilize hydrogen peroxide to catalyze oxidative reactions. A large number of peroxidases have been identified in fungal species and are being characterized at the molecular level. In this manuscript we review the current knowledge on the molecular aspects of this type of enzymes. We present an overview of the research efforts undertaken in deciphering the structural basis of the catalytic properties of fungal peroxidases and discuss molecular genetics and protein homology aspects of this enzyme class. Finally, we summarize the potential biotechnological applications of these enzymes and evaluate recent advances on their expression in heterologous systems for production purposes.


Conesa, Ana Punt, Peter J van den Hondel, Cees A M J J Review Netherlands Journal of biotechnology J Biotechnol. 2002 Feb 14;93(2):143-58.