Projects

Covid-19

CSyF SARS-CoV-2 seguimiento Andalucía

covseq

 

Un consorcio, compuesto por 14 hospitales que cubren todas las provincias de Andalucía, los 5 Institutos de Investigación Sanitaria de Andalucía, la Subdirección Técnica de Gestión de la Información, la Dirección General de Salud Pública (Servicio de Vigilancia Epidemiológica y Salud Laboral) y la Fundación Progreso y Salud, pretende usar la red de centros de diagnóstico de la comunidad Andaluza y los secuenciadores de los Institutos de investigación Sanitaria y centros asociados para secuenciar unas 1.000 muestras del virus SARS-CoV-2 cubriendo toda Andalucía y representado una muestra lo más equilibrada posible de las distintas tipologías de pacientes (edad, sexo, complicaciones previas, tratamientos previos), así como los distintos cuadros clínicos observados y las respuestas a los tratamientos.

Covid-19 drug repurposing

mechanistiCoV

 

Proponemos el uso de un modelo mecanístico basado en inteligencia artificial que ya ha demostrado su efectividad en enfermedades raras para la reutilización de fármacos para Covid-19.

Our Projects

Machine Learning para combatir enfermedades raras (MLDrugRD)

 

The objective of this project is to use Machine Learning to extract information from public genomic repositories that help obtain therapeutic targets or reformulation of existing drugs that help combat or alleviate the pain of rare diseases.

Proyecto Genoma 1000 Navarra (NAGEN 1000)

 

NAGEN: Proyecto Genoma 1000 Navarra (NAGEN 1000) is an initiative led by the Navarrabiomed biomedical research centre whose purpose is to transfer the use of the cutting-edge whole human genome analysis technology to Navarra’s public health care system. To this end, 1,000 genomes of patients with rare diseases and certain types of cancer in the Navarrese Health Service-Osasunbidea (SNS-O) and of their relatives are being analysed.

Undiagnosed Rare Diseases Programme (ENoD)

 

The Program for Undiagnosed Rare diseases, EnoD, is an initiative of CIBERER aimed at improving knowledge about the genetic causes of rare diseases. It entails the discovery of new genes and variants. It is effective through the study of specific clinical cases without molecular diagnostics. To this end, ENoD program places research directly at the service of the National Health System.

ENoD is framed in one of the priority international lines (IRDIRC, H2020) as it is the identification of the genetic causes of rare diseases.

Completed Projects

Medical Genome Project

 

The Medical Genome Project (MGP) was the first regional genomics project carried out in Spain, starting by 2010. MGP was an unprecedented study that has tackled the sequencing of hundreds of human genomes of phenotyped sick individuals and control individuals, to develop the technologies to speed up the laborious process of discovering genes responsible for a given disease. This also means exploring new approaches in the development of diagnostic techniques that allow early detection of these diseases and opens new possibilities for the generation of drugs or therapies that allow their treatment, also at the genetic or cellular level.