|Title||Tools for comparative protein structure modeling and analysis|
|Publication Type||Journal Article|
|Year of Publication||2003|
|Authors||Eswar, N, John, B, Mirkovic, N, Fiser, A, Ilyin, VA, Pieper, U, Stuart, AC, Marti-Renom, MA, Madhusudhan, MS, Yerkovich, B, Sali, A|
|Journal||Nucleic Acids Res|
|Keywords||Amino Acid *Software *Structural Homology; Internet Models; Molecular Protein Folding Proteins/chemistry Reproducibility of Results Sequence Alignment Sequence Homology; Protein Systems Integration|
The following resources for comparative protein structure modeling and analysis are described (http://salilab.org): MODELLER, a program for comparative modeling by satisfaction of spatial restraints; MODWEB, a web server for automated comparative modeling that relies on PSI-BLAST, IMPALA and MODELLER; MODLOOP, a web server for automated loop modeling that relies on MODELLER; MOULDER, a CPU intensive protocol of MODWEB for building comparative models based on distant known structures; MODBASE, a comprehensive database of annotated comparative models for all sequences detectably related to a known structure; MODVIEW, a Netscape plugin for Linux that integrates viewing of multiple sequences and structures; and SNPWEB, a web server for structure-based prediction of the functional impact of a single amino acid substitution.
Eswar, Narayanan John, Bino Mirkovic, Nebojsa Fiser, Andras Ilyin, Valentin A Pieper, Ursula Stuart, Ashley C Marti-Renom, Marc A Madhusudhan, M S Yerkovich, Bozidar Sali, Andrej P50 GM62529/GM/NIGMS NIH HHS/United States R01 GM 54762/GM/NIGMS NIH HHS/United States R33 CA84699/CA/NCI NIH HHS/United States Research Support, Non-U.S. Gov’t Research Support, U.S. Gov’t, P.H.S. England Nucleic acids research Nucleic Acids Res. 2003 Jul 1;31(13):3375-80.