Novel genes detected by transcriptional profiling from whole-blood cells in patients with early onset of acute coronary syndrome: Transcriptional profiling of acute coronary syndrome.

TitleNovel genes detected by transcriptional profiling from whole-blood cells in patients with early onset of acute coronary syndrome: Transcriptional profiling of acute coronary syndrome.
Publication TypeJournal Article
Year of Publication2013
AuthorsSilbiger, VN, Luchessi, AD, Hirata, RDC, Lima-Neto, LG, Cavichioli, D, Carracedo, Á, Brión, M, Dopazo, J, Garcia-Garcia, F, Santos, ESDos, Ramos, RF, Sampaio, MF, Armaganijan, D, Sousa, AGMR, Hirata, MH
JournalClinica chimica acta; international journal of clinical chemistry
Date Published2013 Mar 24
ISSN1873-3492
Abstract

{BACKGROUND: Genome-wide expression analysis using microarrays has been used as a research strategy to discovery new biomarkers and candidate genes for a number of diseases. We aim to find new biomarkers for the prediction of acute coronary syndrome (ACS) with a differentially expressed mRNA profiling approach using whole genomic expression analysis in a peripheral blood cell model from patients with early ACS. METHODS AND RESULTS: This study was carried out in two phases. On phase 1 a restricted clinical criteria (ACS-Ph1

DOI10.1016/j.cca.2013.03.011