| Title | ISACGH: a web-based environment for the analysis of Array CGH and gene expression which includes functional profiling. |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Conde, L, Montaner, D, Burguet-Castell, J, Tárraga, J, Medina, I, Al-Shahrour, F, Dopazo, J |
| Journal | Nucleic Acids Res |
| Volume | 35 |
| Issue | Web Server issue |
| Pagination | W81-5 |
| Date Published | 2007 Jul |
| ISSN | 1362-4962 |
| Keywords | Animals; Cluster Analysis; Computational Biology; Computer Graphics; Gene Expression Profiling; Humans; Internet; Models, Genetic; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Programming Languages; Software; Systems Integration; User-Computer Interface |
| Abstract | We present the ISACGH, a web-based system that allows for the combination of genomic data with gene expression values and provides different options for functional profiling of the regions found. Several visualization options offer a convenient representation of the results. Different efficient methods for accurate estimation of genomic copy number from array-CGH hybridization data have been included in the program. Moreover, the connection to the gene expression analysis package GEPAS allows the use of different facilities for data pre-processing and analysis. A DAS server allows exporting the results to the Ensembl viewer where contextual genomic information can be obtained. The program is freely available at: http://isacgh.bioinfo.cipf.es or within http://www.gepas.org. |
| DOI | 10.1093/nar/gkm257 |
| Alternate Journal | Nucleic Acids Res |
| PubMed ID | 17468499 |
| PubMed Central ID | PMC1933149 |
