Gene expression data preprocessing

TitleGene expression data preprocessing
Publication TypeJournal Article
Year of Publication2003
AuthorsHerrero, J, Diaz-Uriarte, R, Dopazo, J
Keywords*Database Management Systems Gene Expression Profiling/*methods Information Storage and Retrieval/methods Internet Oligonucleotide Array Sequence Analysis/*methods Sequence Alignment/*methods Sequence Analysis; DNA/*methods *Software *User-Computer Interface

We present an interactive web tool for preprocessing microarray gene expression data. It analyses the data, suggests the most appropriate transformations and proceeds with them after user agreement. The normal preprocessing steps include scale transformations, management of missing values, replicate handling, flat pattern filtering and pattern standardization and they are required before performing any pattern analysis. The processed data set can be sent to other pattern analysis tools.


Herrero, J Diaz-Uriarte, R Dopazo, J England Bioinformatics (Oxford, England) Bioinformatics. 2003 Mar 22;19(5):655-6.