Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection.

TitleDrug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection.
Publication TypeJournal Article
Year of Publication2020
AuthorsLoucera, C, Esteban-Medina, M, Rian, K, Falco, MM, Dopazo, J, Peña-Chilet, M
JournalSignal Transduct Target Ther
Volume5
Issue1
Pagination290
Date Published2020 12 11
ISSN2059-3635
KeywordsComputational Chemistry; COVID-19; drug repositioning; Humans; Machine Learning; Molecular Docking Simulation; Molecular Targeted Therapy; Proteins; SARS-CoV-2; Signal Transduction
DOI10.1038/s41392-020-00417-y
Alternate JournalSignal Transduct Target Ther
PubMed ID33311438
PubMed Central IDPMC7729141