@inbook {471, title = {Selective Constraints and Human Disease Genes: Evolutionary and Bioinformatic Approaches}, booktitle = {Encyclopedia of Life Science}, year = {2008}, publisher = {John Wiley \& Sons, Ltd.}, organization = {John Wiley \& Sons, Ltd.}, address = {UK}, doi = {10.1002/9780470015902.a0020762}, author = {H. Dopazo} }