<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mirzayi, Chloe</style></author><author><style face="normal" font="default" size="100%">Renson, Audrey</style></author><author><style face="normal" font="default" size="100%">Zohra, Fatima</style></author><author><style face="normal" font="default" size="100%">Elsafoury, Shaimaa</style></author><author><style face="normal" font="default" size="100%">Geistlinger, Ludwig</style></author><author><style face="normal" font="default" size="100%">Kasselman, Lora J</style></author><author><style face="normal" font="default" size="100%">Eckenrode, Kelly</style></author><author><style face="normal" font="default" size="100%">van de Wijgert, Janneke</style></author><author><style face="normal" font="default" size="100%">Loughman, Amy</style></author><author><style face="normal" font="default" size="100%">Marques, Francine Z</style></author><author><style face="normal" font="default" size="100%">MacIntyre, David A</style></author><author><style face="normal" font="default" size="100%">Arumugam, Manimozhiyan</style></author><author><style face="normal" font="default" size="100%">Azhar, Rimsha</style></author><author><style face="normal" font="default" size="100%">Beghini, Francesco</style></author><author><style face="normal" font="default" size="100%">Bergstrom, Kirk</style></author><author><style face="normal" font="default" size="100%">Bhatt, Ami</style></author><author><style face="normal" font="default" size="100%">Bisanz, Jordan E</style></author><author><style face="normal" font="default" size="100%">Braun, Jonathan</style></author><author><style face="normal" font="default" size="100%">Bravo, Hector Corrada</style></author><author><style face="normal" font="default" size="100%">Buck, Gregory A</style></author><author><style face="normal" font="default" size="100%">Bushman, Frederic</style></author><author><style face="normal" font="default" size="100%">Casero, David</style></author><author><style face="normal" font="default" size="100%">Clarke, Gerard</style></author><author><style face="normal" font="default" size="100%">Collado, Maria Carmen</style></author><author><style face="normal" font="default" size="100%">Cotter, Paul D</style></author><author><style face="normal" font="default" size="100%">Cryan, John F</style></author><author><style face="normal" font="default" size="100%">Demmer, Ryan T</style></author><author><style face="normal" font="default" size="100%">Devkota, Suzanne</style></author><author><style face="normal" font="default" size="100%">Elinav, Eran</style></author><author><style face="normal" font="default" size="100%">Escobar, Juan S</style></author><author><style face="normal" font="default" size="100%">Fettweis, Jennifer</style></author><author><style face="normal" font="default" size="100%">Finn, Robert D</style></author><author><style face="normal" font="default" size="100%">Fodor, Anthony A</style></author><author><style face="normal" font="default" size="100%">Forslund, Sofia</style></author><author><style face="normal" font="default" size="100%">Franke, Andre</style></author><author><style face="normal" font="default" size="100%">Furlanello, Cesare</style></author><author><style face="normal" font="default" size="100%">Gilbert, Jack</style></author><author><style face="normal" font="default" size="100%">Grice, Elizabeth</style></author><author><style face="normal" font="default" size="100%">Haibe-Kains, Benjamin</style></author><author><style face="normal" font="default" size="100%">Handley, Scott</style></author><author><style face="normal" font="default" size="100%">Herd, Pamela</style></author><author><style face="normal" font="default" size="100%">Holmes, Susan</style></author><author><style face="normal" font="default" size="100%">Jacobs, Jonathan P</style></author><author><style face="normal" font="default" size="100%">Karstens, Lisa</style></author><author><style face="normal" font="default" size="100%">Knight, Rob</style></author><author><style face="normal" font="default" size="100%">Knights, Dan</style></author><author><style face="normal" font="default" size="100%">Koren, Omry</style></author><author><style face="normal" font="default" size="100%">Kwon, Douglas S</style></author><author><style face="normal" font="default" size="100%">Langille, Morgan</style></author><author><style face="normal" font="default" size="100%">Lindsay, Brianna</style></author><author><style face="normal" font="default" size="100%">McGovern, Dermot</style></author><author><style face="normal" font="default" size="100%">McHardy, Alice C</style></author><author><style face="normal" font="default" size="100%">McWeeney, Shannon</style></author><author><style face="normal" font="default" size="100%">Mueller, Noel T</style></author><author><style face="normal" font="default" size="100%">Nezi, Luigi</style></author><author><style face="normal" font="default" size="100%">Olm, Matthew</style></author><author><style face="normal" font="default" size="100%">Palm, Noah</style></author><author><style face="normal" font="default" size="100%">Pasolli, Edoardo</style></author><author><style face="normal" font="default" size="100%">Raes, Jeroen</style></author><author><style face="normal" font="default" size="100%">Redinbo, Matthew R</style></author><author><style face="normal" font="default" size="100%">Rühlemann, Malte</style></author><author><style face="normal" font="default" size="100%">Balfour Sartor, R</style></author><author><style face="normal" font="default" size="100%">Schloss, Patrick D</style></author><author><style face="normal" font="default" size="100%">Schriml, Lynn</style></author><author><style face="normal" font="default" size="100%">Segal, Eran</style></author><author><style face="normal" font="default" 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size="100%">Yamada, Takuji</style></author><author><style face="normal" font="default" size="100%">Zeller, Georg</style></author><author><style face="normal" font="default" size="100%">Zhang, Mingyu</style></author><author><style face="normal" font="default" size="100%">Zhao, Ni</style></author><author><style face="normal" font="default" size="100%">Zhao, Liping</style></author><author><style face="normal" font="default" size="100%">Bao, Wenjun</style></author><author><style face="normal" font="default" size="100%">Culhane, Aedin</style></author><author><style face="normal" font="default" size="100%">Devanarayan, Viswanath</style></author><author><style face="normal" font="default" size="100%">Dopazo, Joaquin</style></author><author><style face="normal" font="default" size="100%">Fan, Xiaohui</style></author><author><style face="normal" font="default" size="100%">Fischer, Matthias</style></author><author><style face="normal" font="default" size="100%">Jones, Wendell</style></author><author><style face="normal" font="default" size="100%">Kusko, Rebecca</style></author><author><style face="normal" font="default" size="100%">Mason, Christopher E</style></author><author><style face="normal" font="default" size="100%">Mercer, Tim R</style></author><author><style face="normal" font="default" size="100%">Sansone, Susanna-Assunta</style></author><author><style face="normal" font="default" size="100%">Scherer, Andreas</style></author><author><style face="normal" font="default" size="100%">Shi, Leming</style></author><author><style face="normal" font="default" size="100%">Thakkar, Shraddha</style></author><author><style face="normal" font="default" size="100%">Tong, Weida</style></author><author><style face="normal" font="default" size="100%">Wolfinger, Russ</style></author><author><style face="normal" font="default" size="100%">Hunter, Christopher</style></author><author><style face="normal" font="default" size="100%">Segata, Nicola</style></author><author><style face="normal" font="default" size="100%">Huttenhower, Curtis</style></author><author><style face="normal" font="default" size="100%">Dowd, Jennifer B</style></author><author><style face="normal" font="default" size="100%">Jones, Heidi E</style></author><author><style face="normal" font="default" size="100%">Waldron, Levi</style></author></authors><translated-authors><author><style face="normal" font="default" size="100%">Genomic Standards Consortium</style></author><author><style face="normal" font="default" size="100%">Massive Analysis and Quality Control Society</style></author></translated-authors></contributors><titles><title><style face="normal" font="default" size="100%">Reporting guidelines for human microbiome research: the STORMS checklist.</style></title><secondary-title><style face="normal" font="default" size="100%">Nat Med</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Nat Med</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Computational Biology</style></keyword><keyword><style  face="normal" font="default" size="100%">Dysbiosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Microbiota</style></keyword><keyword><style  face="normal" font="default" size="100%">Observational Studies as Topic</style></keyword><keyword><style  face="normal" font="default" size="100%">Research Design</style></keyword><keyword><style  face="normal" font="default" size="100%">Translational Science, Biomedical</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2021 11</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">27</style></volume><pages><style face="normal" font="default" size="100%">1885-1892</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The particularly interdisciplinary nature of human microbiome research makes the organization and reporting of results spanning epidemiology, biology, bioinformatics, translational medicine and statistics a challenge. Commonly used reporting guidelines for observational or genetic epidemiology studies lack key features specific to microbiome studies. Therefore, a multidisciplinary group of microbiome epidemiology researchers adapted guidelines for observational and genetic studies to culture-independent human microbiome studies, and also developed new reporting elements for laboratory, bioinformatics and statistical analyses tailored to microbiome studies. The resulting tool, called 'Strengthening The Organization and Reporting of Microbiome Studies' (STORMS), is composed of a 17-item checklist organized into six sections that correspond to the typical sections of a scientific publication, presented as an editable table for inclusion in supplementary materials. The STORMS checklist provides guidance for concise and complete reporting of microbiome studies that will facilitate manuscript preparation, peer review, and reader comprehension of publications and comparative analysis of published results.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">11</style></issue><custom1><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/34789871?dopt=Abstract</style></custom1></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Méndez-Salazar, Eder Orlando</style></author><author><style face="normal" font="default" size="100%">Vázquez-Mellado, Janitzia</style></author><author><style face="normal" font="default" size="100%">Casimiro-Soriguer, Carlos S</style></author><author><style face="normal" font="default" size="100%">Dopazo, Joaquin</style></author><author><style face="normal" font="default" size="100%">Cubuk, Cankut</style></author><author><style face="normal" font="default" size="100%">Zamudio-Cuevas, Yessica</style></author><author><style face="normal" font="default" size="100%">Francisco-Balderas, Adriana</style></author><author><style face="normal" font="default" size="100%">Martínez-Flores, Karina</style></author><author><style face="normal" font="default" size="100%">Fernández-Torres, Javier</style></author><author><style face="normal" font="default" size="100%">Lozada-Pérez, Carlos</style></author><author><style face="normal" font="default" size="100%">Pineda, Carlos</style></author><author><style face="normal" font="default" size="100%">Sánchez-González, Austreberto</style></author><author><style face="normal" font="default" size="100%">Silveira, Luis H</style></author><author><style face="normal" font="default" size="100%">Burguete-García, Ana I</style></author><author><style face="normal" font="default" size="100%">Orbe-Orihuela, Citlalli</style></author><author><style face="normal" font="default" size="100%">Lagunas-Martínez, Alfredo</style></author><author><style face="normal" font="default" size="100%">Vazquez-Gomez, Alonso</style></author><author><style face="normal" font="default" size="100%">López-Reyes, Alberto</style></author><author><style face="normal" font="default" size="100%">Palacios-González, Berenice</style></author><author><style face="normal" font="default" size="100%">Martínez-Nava, Gabriela Angélica</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism.</style></title><secondary-title><style face="normal" font="default" size="100%">Mol Med</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Mol Med</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biodiversity</style></keyword><keyword><style  face="normal" font="default" size="100%">Computational Biology</style></keyword><keyword><style  face="normal" font="default" size="100%">Dysbiosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Gastrointestinal Microbiome</style></keyword><keyword><style  face="normal" font="default" size="100%">Gout</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Metagenome</style></keyword><keyword><style  face="normal" font="default" size="100%">metagenomics</style></keyword><keyword><style  face="normal" font="default" size="100%">Protein Interaction Mapping</style></keyword><keyword><style  face="normal" font="default" size="100%">Protein Interaction Maps</style></keyword><keyword><style  face="normal" font="default" size="100%">Uric Acid</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2021 05 24</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">27</style></volume><pages><style face="normal" font="default" size="100%">50</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;b&gt;OBJECTIVE: &lt;/b&gt;To evaluate the taxonomic composition of the gut microbiome in gout patients with and without tophi formation, and predict bacterial functions that might have an impact on urate metabolism.&lt;/p&gt;&lt;p&gt;&lt;b&gt;METHODS: &lt;/b&gt;Hypervariable V3-V4 regions of the bacterial 16S rRNA gene from fecal samples of gout patients with and without tophi (n = 33 and n = 25, respectively) were sequenced and compared to fecal samples from 53 healthy controls. We explored predictive functional profiles using bioinformatics in order to identify differences in taxonomy and metabolic pathways.&lt;/p&gt;&lt;p&gt;&lt;b&gt;RESULTS: &lt;/b&gt;We identified a microbiome characterized by the lowest richness and a higher abundance of Phascolarctobacterium, Bacteroides, Akkermansia, and Ruminococcus_gnavus_group genera in patients with gout without tophi when compared to controls. The Proteobacteria phylum and the Escherichia-Shigella genus were more abundant in patients with tophaceous gout than in controls. Fold change analysis detected nine genera enriched in healthy controls compared to gout groups (Bifidobacterium, Butyricicoccus, Oscillobacter, Ruminococcaceae_UCG_010, Lachnospiraceae_ND2007_group, Haemophilus, Ruminococcus_1, Clostridium_sensu_stricto_1, and Ruminococcaceae_UGC_013). We found that the core microbiota of both gout groups shared Bacteroides caccae, Bacteroides stercoris ATCC 43183, and Bacteroides coprocola DSM 17136. These bacteria might perform functions linked to one-carbon metabolism, nucleotide binding, amino acid biosynthesis, and purine biosynthesis. Finally, we observed differences in key bacterial enzymes involved in urate synthesis, degradation, and elimination.&lt;/p&gt;&lt;p&gt;&lt;b&gt;CONCLUSION: &lt;/b&gt;Our findings revealed that taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><custom1><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/34030623?dopt=Abstract</style></custom1></record></records></xml>