<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dopazo, J.</style></author><author><style face="normal" font="default" size="100%">Mendoza, A.</style></author><author><style face="normal" font="default" size="100%">Herrero, J.</style></author><author><style face="normal" font="default" size="100%">Caldara, F.</style></author><author><style face="normal" font="default" size="100%">Humbert, Y.</style></author><author><style face="normal" font="default" size="100%">Friedli, L.</style></author><author><style face="normal" font="default" size="100%">Guerrier, M.</style></author><author><style face="normal" font="default" size="100%">Grand-Schenk, E.</style></author><author><style face="normal" font="default" size="100%">Gandin, C.</style></author><author><style face="normal" font="default" size="100%">de Francesco, M.</style></author><author><style face="normal" font="default" size="100%">Polissi, A.</style></author><author><style face="normal" font="default" size="100%">Buell, G.</style></author><author><style face="normal" font="default" size="100%">Feger, G.</style></author><author><style face="normal" font="default" size="100%">Garcia, E.</style></author><author><style face="normal" font="default" size="100%">Peitsch, M.</style></author><author><style face="normal" font="default" size="100%">Garcia-Bustos, J. F.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Annotated draft genomic sequence from a Streptococcus pneumoniae type 19F clinical isolate</style></title><secondary-title><style face="normal" font="default" size="100%">Microb Drug Resist</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bacterial Molecular Sequence Data Pneumococcal Infections/*microbiology Prokaryotic Cells RNA</style></keyword><keyword><style  face="normal" font="default" size="100%">Bacterial/chemistry/genetics Genes</style></keyword><keyword><style  face="normal" font="default" size="100%">Bacterial/genetics *Genome</style></keyword><keyword><style  face="normal" font="default" size="100%">DNA</style></keyword><keyword><style  face="normal" font="default" size="100%">Transfer/metabolism Streptococcus pneumoniae/*genetics</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2001</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Citation&amp;list_uids=11442348</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">2</style></number><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">99-125</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">The public availability of numerous microbial genomes is enabling the analysis of bacterial biology in great detail and with an unprecedented, organism-wide and taxon-wide, broad scope. Streptococcus pneumoniae is one of the most important bacterial pathogens throughout the world. We present here sequences and functional annotations for 2.1-Mbp of pneumococcal DNA, covering more than 90% of the total estimated size of the genome. The sequenced strain is a clinical isolate resistant to macrolides and tetracycline. It carries a type 19F capsular locus, but multilocus sequence typing for several conserved genetic loci suggests that the strain sequenced belongs to a pneumococcal lineage that most often expresses a serotype 15 capsular polysaccharide. A total of 2,046 putative open reading frames (ORFs) longer than 100 amino acids were identified (average of 1,009 bp per ORF), including all described two-component systems and aminoacyl tRNA synthetases. Comparisons to other complete, or nearly complete, bacterial genomes were made and are presented in a graphical form for all the predicted proteins.</style></abstract><notes><style face="normal" font="default" size="100%">Dopazo, J Mendoza, A Herrero, J Caldara, F Humbert, Y Friedli, L Guerrier, M Grand-Schenk, E Gandin, C de Francesco, M Polissi, A Buell, G Feger, G Garcia, E Peitsch, M Garcia-Bustos, J F United States Microbial drug resistance (Larchmont, N.Y.) Microb Drug Resist. 2001 Summer;7(2):99-125.</style></notes></record></records></xml>