<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Herrero, J.</style></author><author><style face="normal" font="default" size="100%">Dopazo, J.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Combining hierarchical clustering and self-organizing maps for exploratory analysis of gene expression patterns</style></title><secondary-title><style face="normal" font="default" size="100%">J Proteome Res</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cluster Analysis Computational Biology/methods *Gene Expression Genes</style></keyword><keyword><style  face="normal" font="default" size="100%">Fungal/genetics *Genome Oligonucleotide Array Sequence Analysis/*methods Statistics as Topic/*methods Time Factors</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2002</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Citation&amp;list_uids=12645919</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">5</style></number><volume><style face="normal" font="default" size="100%">1</style></volume><pages><style face="normal" font="default" size="100%">467-70</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Self-organizing maps (SOM) constitute an alternative to classical clustering methods because of its linear run times and superior performance to deal with noisy data. Nevertheless, the clustering obtained with SOM is dependent on the relative sizes of the clusters. Here, we show how the combination of SOM with hierarchical clustering methods constitutes an excellent tool for exploratory analysis of massive data like DNA microarray expression patterns.</style></abstract><notes><style face="normal" font="default" size="100%">Herrero, Javier Dopazo, Joaquin Research Support, Non-U.S. Gov’t United States Journal of proteome research J Proteome Res. 2002 Sep-Oct;1(5):467-70.</style></notes></record></records></xml>