01733nas a2200193   4500008004100000022001400041245017100055210006900226260001600295520097200311100001801283700001601301700001801317700002101335700001801356700002201374700001801396856012501414       2012                        eng d  a1364-370300aMicroarray analysis of Etrog citron (Citrus medica L.) reveals changes in chloroplast, cell wall, peroxidase and symporter activities in response to viroid infection.0 aMicroarray analysis of Etrog citron Citrus medica L reveals chan  c2012 Mar 153 aViroids are small (246-401 nucleotides), single-stranded, circular RNA molecules that infect several crop plants and can cause diseases of economic importance. Citrus are the hosts in which the largest number of viroids have been identified. Citrus exocortis viroid (CEVd), the causal agent of citrus exocortis disease, induces considerable losses in citrus crops. Changes in the gene expression profile during the early (pre-symptomatic) and late (post-symptomatic) stages of Etrog citron infected with CEVd were investigated using a citrus cDNA microarray. MaSigPro analysis was performed and, on the basis of gene expression profiles as a function of the time after infection, the differentially expressed genes were classified into five clusters. FatiScan analysis revealed significant enrichment of functional categories for each cluster, indicating that viroid infection triggers important changes in chloroplast, cell wall, peroxidase and symporter activities.1 aRizza, Serena1 aConesa, Ana1 aJuarez, José1 aCatara, Antonino1 aNavarro, Luis1 aDuran-Vila, Nuria1 aAncillo, Gema  uhttp://clinbioinfosspa.es/content/microarray-analysis-etrog-citron-citrus-medica-l-reveals-changes-chloroplast-cell-wall