@article {552,
	title = {Functional genomics and networks: new approaches in the extraction of complex gene modules.},
	journal = {Expert Rev Proteomics},
	volume = {7},
	year = {2010},
	month = {2010 Feb},
	pages = {55-63},
	abstract = {<p>The engine that makes the cell work is made of an intricate network of molecular interactions. Nowadays, the elements and relationships of this complex network can be studied with several types of high-throughput techniques. The dream of having a global picture of the cell from different perspectives that can jointly explain cell behavior is, at least technically, feasible. However, this task can only be accomplished by filling the gap between data and information. The availability of methods capable of accurately managing, integrating and analyzing the results from these experiments is crucial for this purpose. Here, we review the new challenges raised by the availability of different genomic data, as well as the new proposals presented to cope with the increasing data complexity. Special emphasis is given to approaches that explore the transcriptome trying to describe the modules of genes that account for the traits studied.</p>},
	keywords = {Gene Expression Regulation, Gene Regulatory Networks, Genomics, Protein Binding, Proteins, Systems biology},
	issn = {1744-8387},
	doi = {10.1586/epr.09.103},
	author = {Minguez, Pablo and Dopazo, Joaquin}
}
