@article {1162,
	title = {Concurrent and Accurate Short Read Mapping on Multicore Processors.},
	journal = {IEEE/ACM transactions on computational biology and bioinformatics / IEEE, ACM},
	volume = {12},
	year = {2015},
	month = {2015 Sep-Oct},
	pages = {995-1007},
	abstract = {We introduce a parallel aligner with a work-flow organization for fast and accurate mapping of RNA sequences on servers equipped with multicore processors. Our software, [Formula: see text] ([Formula: see text] is an open-source application. The software is available at http://www.opencb.org, exploits a suffix array to rapidly map a large fraction of the RNA fragments (reads), as well as leverages the accuracy of the Smith-Waterman algorithm to deal with conflictive reads. The aligner is enhanced with a careful strategy to detect splice junctions based on an adaptive division of RNA reads into small segments (or seeds), which are then mapped onto a number of candidate alignment locations, providing crucial information for the successful alignment of the complete reads. The experimental results on a platform with Intel multicore technology report the parallel performance of [Formula: see text], on RNA reads of 100-400 nucleotides, which excels in execution time/sensitivity to state-of-the-art aligners such as TopHat 2+Bowtie 2, MapSplice, and STAR.},
	keywords = {HPC, NGS, short real mapping},
	issn = {1557-9964},
	doi = {10.1109/TCBB.2015.2392077},
	url = {http://ieeexplore.ieee.org/xpl/articleDetails.jsp?tp=\&arnumber=7010005},
	author = {Martinez, Hector and T{\'a}rraga, Joaqu{\'\i}n and Medina, Ignacio and Barrachina, Sergio and Castillo, Maribel and Dopazo, Joaquin and Quintana-Orti, Enrique S}
}
